The Filippi lab is recruiting a motivated postdoctoral fellow with interest and expertise in Hematopoiesis and Hematopoietic Stem Cell functions. Our laboratory has several exiting projects focusing on the regulation of hematopoietic stem cell (HSC) self-renewal under regenerative conditions and during aging. We are addressing fundamental and important questions about the role of stress signaling pathways, mitochondrial metabolism and innate immune signaling on HSC functions, how these pathways contribute to the functional decline of the hematopoietic system after regenerative stress and how these stress-related pathways contribute to secondary neoplasms, including bone marrow failure and myelodysplastic syndromes. The lab uses state-of-the-art imaging technologies, multi-omics approaches, extensive mouse models and patient specimen.
MAJOR DUTIES AND RESPONSIBILITIES: ??? Design, execute, and record laboratory experiments, and analyze the data. ??? Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department. ??? Present research at laboratory meetings, journal clubs, seminars, and meetings. ??? Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants. ??? Maintain currency in field through continuing education, literature, and seminars. ??? Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all policies and procedures. ??? Perform other duties as assigned.
Cincinnati Children's Research and Training at a Glance
Among the top in NIH funding for pediatric research institutions
Over 1.4 million square feet of research laboratory space
900+ scientists conducting basic, translational, and clinical research
Over 2000 publications annually in top-tier journals
Access to Employee Resource Groups and Mentorship programs
Postdocs have gone on to careers in academia, biotech, pharma, teaching etc.
EDUCATION\WORK EXPERIENCE: Ph.D. in related discipline, MD, or equivalent required. Candidates must hold a Ph.D. and/or M.D. degree and should possess strong laboratory and analytical skills, and record of peer-reviewed publications. Applicants with prior experience in hematopoiesis and stem cell biology are particularly encouraged to apply, but we will also consider candidates with strong backgrounds in immunology, cellular biology, imaging, and cancer biology.
REQUIRED SKILLS: Excellent written, verbal, and interpersonal communication skills. Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design. Computer literate and working knowledge of software applications (word processing, spreadsheet, and database). Analytical ability sufficient to compare data; mathematical ability sufficient to perform algebraic calculations and statistical analysis. Ability to synthesize information and to create and deal with new situations by applying past experiences. Expressed willingness to teach others and share results. Capable of meeting time demands necessary to execute experiments.
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better, and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.